関連する実験動画

Updated: Mar 31, 2026

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET

Published on: August 17, 2022

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2つのFGF-FGFR複合体の結晶構造は,リガンド受容体特異性の決定因子を明らかにします

A N Plotnikov1, S R Hubbard, J Schlessinger

  • 1Department of Pharmacology, New York University School of Medicine, New York 10016, USA.

Cell
|June 1, 2000
PubMed
まとめ

構造分析により,線維芽細胞成長因子 (FGF) がFGF受容体 (FGFRs) にどのように結合するかが明らかになります. 特殊性は,FGFRの代替スプライス変種と相互作用するユニークなFGF領域から生じ,さまざまなシグナリング結果を説明します.

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