イディオパシー限定性心筋病症の臨床プロファイルと結果
N M Ammash1, J B Seward, K R Bailey
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn. 55905, USA.
Circulation
|June 1, 2000
まとめ
イディオパシー・リストリクティブ・カルディオミオパシーとは,心室が膨張せず,心房が膨張した心疾患で,予後が悪い. 死亡の危険因子には,男性,高齢,心不全の症状が進行していることが含まれる.
科学分野:
- 心臓病学 心臓病学
- 心血管医学は,心臓血管医学である.
- エコーカルディオグラフィー エコーカルディオグラフィー
背景:
- Idiopathic restrictive cardiomyopathy (IRC) は,あまり認識されていない心臓病である.
- 特徴は正常な心室の大きさ/厚さ,下静脈機能不全,心房の拡大です.
- 変形性シストリック機能を持つ原因不明.
研究 の 目的:
- IRC.のためのエコーカルディオグラフィの基準を定義する.
- IRC患者の臨床表現と予後を評価する.
- IRCにおける死亡率に関連するリスク要因を特定する.
主な方法:
- IRC (1979-1996) の厳格なエコーカルディオグラフィク基準を満たした94人の患者の遡及的分析.
- 既知の浸透性疾患または高血圧を有する患者の除外.
- 生存分析とリスク因子の特定のために収集されたフォローアップデータ.
主要な成果:
- この研究では,IRCを患っている94人の患者,主に女性,平均年齢64歳を特定しました.
- 動脈動 (74%) と収縮性機能障害 (16%) が一般的であった.
- 患者の50%が平均68ヶ月の追跡期間中に死亡し,死亡率は予想よりも大幅に高かった.
結論:
- IRCは,エコーカルディオグラフィによって,腹腔の拡張を伴う非膨張,非高縮性心室として定義され,さまざまな年齢層に影響するが,主に高齢者に影響する.
- 静脈閉塞と心房細動を呈する患者は,予後が悪いことを示す.
- 死亡率の主要な予測要因には,男性の性別,年齢>70,より高いNYHAクラス,および左心房寸法>60mmが含まれています.
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