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Updated: Aug 14, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
11:44

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

細胞生存とNF-kappaB活性化におけるグリコゲン合成酵素キナーゼ-3βの要件

K P Hoeflich1, J Luo, E A Rubie

  • 1Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Canada.

Nature
|July 14, 2000
PubMed
まとめ

グリコーゲン合成キナーゼ-3β (GSK-3β) 欠乏症は,過剰な腫瘍死滅因子 (TNF) 毒性による肝損傷による胚死亡を引き起こす. GSK-3βは核因子-kappaB (NF-kappaB) 機能を促進し,TNF誘発細胞死から保護する.

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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

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