関連する実験動画
Updated: Jul 7, 2026

10:32
Mechanical Testing of Mouse Carotid Arteries: from Newborn to Adult
Published on: February 23, 2012
若年成人における出生サイズと動脈コンプライアンス
Lancet (London, England)
|July 21, 2000
まとめ
低出生体重は,成人期における動脈硬直を予測するものではありません. この研究では,成人における出生サイズと動脈脈波速度の間には関連性がないことが判明し,他の要因が人生の後半に心血管の健康に影響を及ぼすことを示唆しています.
科学分野:
- 心血管の生理学 心血管の生理学
- 健康と病気の発達の起源は,健康と病気の発達の起源である.
背景:
- 胎児の成長障害は,大動脈の順守に影響を与え,個人を高血圧に誘発すると仮定されています.
- 脈波速度で測定される動脈の硬さは,心血管リスクの重要な指標です.
研究 の 目的:
- 成人期における出生サイズと動脈の硬さとの関連を調査する.
- 生まれた時のサイズが25歳の時のパルス波速度に影響するかどうかを判断するためです.
主な方法:
- 出産時のサイズと動脈脈波速度を評価する縦断的な研究.
- 分析対象は25歳の男女でした.
主要な成果:
- 低出生サイズと動脈脈波速度との間に有意な関連性は見つかりませんでした.
- 生まれのサイズと大人のサイズとの相互作用は,パルス波速度と相関しませんでした.
結論:
- 出産時のサイズだけでは,25歳で動脈の硬直を予測することはないようです.
- 胎児の成長による長期的な心血管疾患の影響を理解するために,さらなる研究が必要である.
関連する概念動画
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Assessment of blood pressure in brachial artery(one-step method)
This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Prepare for the Procedure:
Assessment of blood pressure in brachial artery(two-step method)
Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
Arteries and Arterioles
Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles and...
Autoregulation of Blood Flow
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Development of Blood Vessels
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...

