感情調節の神経回路の機能障害は,暴力への前奏となる可能性がある
R J Davidson1, K M Putnam, C L Larson
1Laboratory for Affective Neuroscience and W. M. Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, WI 53706, USA. rjdavids@facstaff.wisc.edu
まとめ
遺伝学と環境の影響を受けた脳の感情調節の欠陥は,衝動的な攻撃性と暴力に関連しています. 前頭前皮質の機能不全のセロトニン経路は,このリスクを高める可能性があります.
科学分野:
- 神経科学は神経科学である.
- 精神科医は精神病を患っている.
- 行動科学は,行動科学である.
背景:
- 感情の調節には,軌道前頭皮質,桃体,前帯状皮質を含む複雑な脳回路が関与しています.
- 遺伝的要因と環境的要因の両方が,この神経回路の発達と機能に影響します.
- 感情の調節障害は,衝動的な攻撃性と暴力の根底にあると仮定されています.
研究 の 目的:
- 誤った感情調節の神経基礎を探求するため.
- 前頭前皮質のセロトナージック投影と衝動的暴力との関連を調査する.
- リスク集団に対する潜在的な介入目標の特定.
主な方法:
- 感情調節回路に関する既存の研究のレビュー.
- 攻撃性と暴力に関連する神経生物学的発見の分析.
- 前頭前皮質におけるセロトナーギー経路の役割の検討.
主要な成果:
- 機能障害のある感情調節回路,特に前頭前皮質が関与することは,衝動的攻撃と関連しています.
- 前頭前皮質へのセロトナージック投影の変化は,衝動的暴力を持つ個体で観察されています.
- 負の感情の誤った調節に対する脆弱性は,攻撃的行動のリスクを増やす.
結論:
- 感情の調節に欠陥があることは,衝動的な攻撃性と暴力に寄与する重要な要因です.
- 前頭前皮質にあるセロトナーギー系は,衝動的行動を調節する上で重要な役割を果たします.
- 感情の調節の神経回路を理解することは,リスクのある個人に介入するための新しい経路を提供します.
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