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Updated: May 11, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

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Published on: October 8, 2012

CD3デルタカップルのT細胞受容体は,ERK活性化とチモサイト陽性選択にシグナルを送信します

P Delgado1, E Fernández, V Dave

  • 1Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Spain.

Nature
|August 10, 2000
PubMed
まとめ

T細胞の発達には,適切なT細胞受容体 (TCR) 信号伝達のためにCD3デルタ鎖が必要です. CD3デルタ欠乏は,成熟T細胞の分化に不可欠なチモサイトにおけるERK活性化と陽性選択を阻害する.

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