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Updated: Mar 19, 2026

Manipulation and Analysis of Cell Cycle-Dependent Processes in Budding Yeast
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Chfrは,メタフェーズへのエントリーを遅らせるミトのストレスチェックポイントを定義します

D M Scolnick1, T D Halazonetis

  • 1The Wistar Institute, Philadelphia, Pennsylvania 19104-4268, USA.

Nature
|August 10, 2000
PubMed
まとめ

CHFR遺伝子は重要なチェックポイントとして機能し,ミトーシスストレス下で細胞サイクルがメタフェーズに入るのを遅らせます. がん細胞におけるその不活性化は,この遅延を危うくし,がん治療戦略に影響を与える.

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