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Updated: Jul 12, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

刺激による鎮痛:モルヒネに対する耐性および相互耐性の発達

D J Mayer, R L Hayes

    Science (New York, N.Y.)
    |May 30, 1975
    PubMed
    まとめ

    繰り返された脳刺激は,痛みを和らげる効果に対する耐性を引き起こすが,これは休憩後に逆転する. モルヒネ依存症はまた,刺激によって引き起こされる疼痛緩和を減少させ,共有された疼痛制御メカニズムを示唆します.

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