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Updated: Jul 11, 2026

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サイクロオキシゲネーゼ-1および-2に依存したプロスタサイクリン形成は,動脈硬化症の患者において発生する

O Belton1, D Byrne, D Kearney

  • 1Department of Clinical Pharmacology and Surgery, Royal College of Surgeons in Ireland, St Stephens Green, Dublin, Ireland.

Circulation
|August 23, 2000
PubMed
まとめ

サイクロオキシゲナーゼ-2 (COX-2) とCOX-1は,動脈硬化症におけるプロスタサイクリン (PGI) の増加に寄与する. トロンボキサンA ((2) (TXA ((2)) は主にCOX-1によって生成され,ニメスリドはPGI ((2) を減少させるが,TXA ((2) を減少させない.

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