男性における身体活動と冠動脈疾患: ハーバード大学院生健康調査
H D Sesso1, R S Paffenbarger, I M Lee
1Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA. hsesso@hsph.harvard.edu
Circulation
|August 30, 2000
まとめ
定期的な身体活動,特に激しい運動を行うことは,冠動脈疾患 (CHD) のリスクを大幅に低下させます. この利点は,心臓病のリスク要因が複数ある個人にさえも及ぶ.
科学分野:
- 心血管の健康についてです.
- 運動生理学 運動生理学
- 予防性心臓病学 予防性心臓病学
背景:
- 冠動脈性心疾患 (CHD) の第一予防のための正確な身体活動レベルはよく定義されていません.
- 身体活動の強さと量が心血管疾患のリスクに与える影響を理解することは極めて重要です.
研究 の 目的:
- 身体活動の量と強さと,心血管疾患を発症するリスクとの関連を調査する.
- この関連が他の既知の冠動脈リスク因子によって変化しているかどうかを判断する.
主な方法:
- 中年および高齢の男性12,516人のコホートは,1977年から1993年まで追跡された.
- 身体的活動は,散歩,階段を登り,スポーツから得られた週1キロジュール (kJ/wk) を用いて,ベースラインで定量化されました.
- インシデントCHDイベントは,フォローアップ期間中に注意深く記録されました.
主要な成果:
- 全体的な身体活動のレベルが高くなったと,心血管疾患のリスクが低下した (P for trend=0.003).
- 具体的には,スポーツ/レクリエーション・アクティビティと活発なアクティビティの合計は,CHDリスクと有意な逆相関を示した (P for trend=0.042とP=0.02,それぞれ).
- 複数の冠動脈リスク因子を持つ男性は,より高い身体活動レベル (>/=4,200 kJ/w) とともに,心血管疾患のリスクも低下しました.
結論:
- 全体的な身体活動と激しい強度の活動の両方が,冠動脈疾患のリスクを減らすための鍵です.
- 心血管疾患に対する身体活動の保護的関連は,複数の心血管疾患の危険因子を持つ男性でも明らかです.
- 適度なおよび軽度の活動は,非有意な逆相関を示し,活発な活動は,より影響力のあるまたは正確に測定される可能性があることを示唆しました.
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