架空の髄膜炎. 架空の髄膜炎. 架空の髄膜炎. 架空の髄膜炎. 商用腰椎間板穿刺用トレイの生命力のない細菌による診断エラー
JAMA
|August 25, 1975
まとめ
汚染された脳脊髄液 (CSF) のサンプル管は,細菌性髄膜炎を模倣した偽陽性グラムステインを引き起こす可能性があります. この汚染は,正確な患者ケアを確保するために,診断材料の慎重な評価を必要とします.
科学分野:
- クリニカルマイクロバイオロジー
- 診断病理学的病理学について
- 感染症 感染症は感染症です.
背景:
- 5つの偽陽性脳脊髄液 (CSF) のグラムステインの連続は,潜在的な汚染源の調査を促した.
- バクテリア性髄膜炎のような深刻な感染症の診断における偽陽性結果の臨床的影響は著しい.
研究 の 目的:
- CSF標本における繰り返し発生する偽陽性グラム染色結果の原因を特定するために.
- 商業用腰部刺用トレイが細菌汚染の源であるかどうかを判断するために.
主な方法:
- 商用品の腰椎間板穿刺用トレイを検査しました.
- 試料管は試験溶液で満たされ,CSFのサンプルと同様に処理された.
- 微生物の存在を検出するために,加工された溶液にグラムステインが行われました.
主要な成果:
- 非活性の細菌は,商用腰椎穿刺用トレイからのサンプルチューブで検出されました.
- 評価された12本のチューブのうち10本のチューブが,加工されたとき,グラム陰性棒,ディプロコッシー,またはコココバシリを含むグラム染料を生成しました.
- バクテリア性髄膜炎を最初治療した患者は,偽陽性の結果から治療を受けていた.
結論:
- 商用CSFサンプルチューブの微生物による汚染は,診断エラーの潜在的な原因です.
- 汚染された管からの発見は,初期の細菌性髄膜炎をシミュレートすることができ,誤診と不適切な治療につながる.
- 医療施設は,患者に害を及ぼすのを防ぐために,診断用品の不妊性に関して警戒すべきである.
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