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Updated: Jul 10, 2026

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides
16:42

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides

Published on: November 24, 2010

サイトプラズマから輸入されたtRNAによってミトコンドリアDNAの突然変異を抑制する

O A Kolesnikova1, N S Entelis, H Mireau

  • 1FRE 2168 du CNRS, Mécanismes Moléculaires de la Division Cellulaire et du Développement, 21 rue René Descartes, 67084 Strasbourg, France.

Science (New York, N.Y.)
|September 16, 2000
PubMed
まとめ

研究者は,ミトコンドリアの遺伝的欠陥を修正するために,トランスファーRNA (tRNA) 輸入を用いて調査した. 彼らは,改変されたtRNAがミトコンドリアに入り,ヒトの細胞でさえ機能し,呼吸器系問題を修正できることを実証しました.

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