関連する実験動画
Updated: May 14, 2026
12:30
Monitoring ER/SR Calcium Release with the Targeted Ca2+ Sensor CatchER+
Published on: May 19, 2017
カルシウムサプリメントの鉛含有量
E A Ross1, N J Szabo, I R Tebbett
1End-Stage Renal Disease Program, Division of Nephrology, Hypertension, and Transplantation, University of Florida, Box 100224, Gainesville, FL 32610-0224, USA. Rossea@medicine.ufl.edu
JAMA
|September 16, 2000
まとめ
天然および精製されたタイプを含む多くのカルシウムサプリメントには,懸念されるレベルの鉛が含まれています. これは,特に骨粗鬆症や腎臓疾患のために高用量薬を服用している個人に,避けられる公衆衛生上のリスクをもたらします.
科学分野:
- 環境衛生 環境衛生 環境衛生
- 毒理学 毒理学 毒理学
- 栄養科学とは,栄養科学である.
背景:
- 天然および精製された配方を含む非処方カルシウムサプリメントは,有意な鉛濃度が含まれていることが判明しました.
- 骨粗鬆症の予防と治療のためのカルシウムに対する医師の勧告の増加は,鉛のような潜在的な汚染物質の検査を必要とします.
研究 の 目的:
- 様々なカルシウムサプリメントの鉛含有量を測定するために.
- 子供,骨粗鬆症の治療,および透析患者のために適切な用量で,人気のあるカルシウムブランドからの潜在的鉛暴露を定量化するために.
主な方法:
- 21種類の非処方カルシウム炭酸 (7種類は天然,14種類は精製),1種類は処方カルシウムアセテート,1種類はリン酸結合剤の鉛含有量の分析.
- 鉛含有量は,電熱的原子吸収を用いて測定され,異なる元素カルシウム摂取量で1日あたりマイクログラムの鉛で表現されました.
主要な成果:
- 7つの天然カルシウム製品のうち4つが測定可能な鉛を示し,腎臓用投与で最大10マイクログラム/日までの毎日の暴露を示した.
- 14種類の精製製品のうち4種類は鉛を含み,骨粗鬆症の投与量では最大3マイクログラム/日,腎臓の投与量では最大20マイクログラム/日までの日々の被曝が認められた.
- カルシウムアセテートや合成リン酸結合剤製品に鉛は検出されなかった.
結論:
- 多くのカルシウムサプリメントの配合には鉛が含まれ,容易に回避可能な公衆衛生上の懸念を示しています.
- 厳格な鉛曝露制限にもかかわらず,サプリメント中の汚染は,注意を必要とする問題であり続けています.
関連する概念動画
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01:21Skeleton and Calcium Homeostasis
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