全粒粉の消費と女性の不全性脳卒中のリスク: 展望的研究
S Liu1, J E Manson, M J Stampfer
1Division of Preventive Medicine, Bringham and Women's Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA. simin.liu@channing.harvard.edu
JAMA
|September 23, 2000
まとめ
全体の穀物摂取量の増加は,女性における缺血性脳卒中のリスクの低下と関連しています. これらの発見は,心血管疾患の予防のために全粒穀物を食事に組み込むことを支持しています.
科学分野:
- エピデミオロジー エピデミオロジー
- 栄養科学 栄養学 栄養科学は,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学は,栄養学が,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は
- 心血管の健康について
背景:
- 食事の推奨は,しばしば心血管疾患 (CVD) の予防のために穀物製品の摂取量を増加することを示唆しています.
- しかし,全粒穀物の消費と,特に女性における,不全性脳卒中のリスクとの特定の関係に関する予測データには,限られたものがあります.
研究 の 目的:
- 全粒穀物の消費量が増加すると,女性の脳卒中リスクが低下するという仮説を検証する.
主な方法:
- 看護師の健康研究から75,521人の米国女性 (38~63歳) を対象とした前向きなコホート研究.
- 参加者は1984年から1994年まで詳細な食品頻度アンケート (FFQ) を記入し,12年間追跡調査を行った.
- 低血圧性脳卒中の発生率は,医療記録を通じて確認され,全粒穀物の摂取量のクインチルによって分析されました.
主要な成果:
- フォローアップ期間 (861,900人年) で,352例の缺血性脳卒中が確認されました.
- 全粒穀物の摂取量と不全性脳卒中のリスク (P=.003 for trend) の間には逆の関連性が見られた.
- この関連性は,喫煙,CVDリスク要因,飽和脂肪,およびトランス脂肪酸の摂取量を調整した後も持続しました.
結論:
- 全粒穀物食品の摂取量が増えることは,女性における缺血性脳卒中のリスクの低下と関連しています.
- この関係は,既定の心血管疾患の危険因子とは無関係です.
- この発見は,全粒穀物の潜在的役割が,不全性脳卒中のリスクを軽減する可能性を裏付けるものである.
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