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Updated: May 1, 2026

Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase
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Protein Film Infrared Electrochemistry Demonstrated for Study of H2 Oxidation by a [NiFe] Hydrogenase

Published on: December 4, 2017

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タイロシジン合成酵素のチオエステラーゼドメインによって触媒化されたペプチドサイクリング

J W Trauger1, R M Kohli, H D Mootz

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 23, 2000
PubMed
まとめ

この研究は,切除されたチオエステラーゼ (TE) ドメインがペプチド-チオエステルのマクロサイクリングを独立して触媒化できることを示しています. この発見は,TE基板の特異性を理解し,新しい天然製品バイオシンセシスを設計するために不可欠です.

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