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Updated: May 9, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

ミトーシス遺伝子発現におけるクロマチンの改造酵素の世界的役割

J E Krebs1, C J Fry, M L Samuels

  • 1Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01605, USA.

Cell
|September 28, 2000
PubMed
まとめ

ATP依存クロマチン改造酵素 (SWI/SNF) は,ミトーシス中の遺伝子発現のためにヒストンアセチルトランスフェラーゼ (Gcn5p) の徴募を制御する. このプロセスは,ミトスの脱出と凝縮されたミトスの染色体内の遺伝子調節に不可欠です.

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Spreading of Chromatin Modifications

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Writers
The writer is an enzyme that can...
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Chromatin Position Affects Gene Expression

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The 3-dimensional positioning of chromatin in the nucleus influences the timing and level of...
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In eukaryotic cells, nascent mRNA transcripts need to undergo many post-transcriptional modifications to reach the cell cytoplasm and translate into functional proteins. For a long time, transcription and pre-mRNA processing were considered two independent events that occur sequentially in the cell. However, it has now been well established that transcription and pre-mRNA processing are two simultaneous processes that are precisely regulated inside the cell.
The chromatin structure, especially...
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Duplication of Chromatin Structure

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Chromatin Modification in iPS Cells

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Compact chromatin makes reprogramming difficult. Enzymes, such as histone demethylases and acetyltransferases, are often added during reprogramming to loosen the chromatin, making the DNA more accessible to transcription factors. Molecules that inhibit histone...