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Updated: Jun 12, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

A20欠乏マウスにおけるTNF誘発のNF-kappaBと細胞死反応の制御に失敗した

E G Lee1, D L Boone, S Chai

  • 1Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, MC 6084, Chicago, IL 60637, USA.

Science (New York, N.Y.)
|September 29, 2000
PubMed
まとめ

A20タンパク質は,腫瘍死滅因子 (TNF) 誘発核因子カッパB (NF-kappaB) 反応を停止することによって,炎症を抑制します. A20が欠けているマウスは,A20を強調して,重度の炎症と細胞死亡の増加を示します.

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A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces

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