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心房の電気的改造は,パラキシズム性および慢性心房と関連しています
P B Sparks1, S Jayaprakash, J K Vohra
1Royal Melbourne Hospital Department of Cardiology and the University of Melbourne, Department of Medicine, Melbourne, Australia.
Circulation
|October 12, 2000
まとめ
パロキシズム性心房 (AFL) と慢性性心房の両方が,心房の可逆的な電気的改造を誘発する. しかし,回復パターンは,この2つの条件の間に異なっています.
科学分野:
- 心臓病学 心臓病学
- 電気生理学 電気生理学
- アトリアルリズム不調症 アトリアルリズム不調症
背景:
- 心房の電気再構築は,心房不律症の発生と持続に関与しています.
- 心臓の電気再構築に寄与性心房振動 (AFL) と慢性心房振動 (AFL) の特異的な影響は不明である.
研究 の 目的:
- パロキシズム性AFLおよび慢性AFLの患者における心房電気再構成の存在と特徴を調査する.
- パロキシズム性AFLと慢性AFLの終了後の電気再構築回復の時間経過を比較する.
主な方法:
- 評価された効果的耐火期 (ERP) と修正されたシヌスノード回復時間 (cSNRT) は,誘発フラッター前後のパロキシズマルAFL患者,およびアブレーション前後のさまざまな時間点における慢性AFL患者で評価された.
- 電気的特性を分離するために,自律的封鎖の下で測定を行った.
主要な成果:
- パロキシズマ性AFLによって誘発された,横側右心房 (LRA) のERPが一時的に減少し,約5分以内に回復した.
- 慢性AFLは,前回の時点と比較して3週間後にERPを大幅に延長し,cSNRTを減少させた.
- 心房細動は,AFLの間,または屈折性が最も低いとき,一部の患者で発生しました.
結論:
- パロキシズム性および慢性AFLの両方が,心房の可逆的な電気的改造を引き起こします.
- この改造の回復のダイナミクスは,症候性AFLと慢性AFLの間で有意に異なっており,慢性AFLはより長期的な影響を示しています.
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