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Glial Cells01:04

Glial Cells

Overview
Anatomy of the Brain: Major Regions01:20

Anatomy of the Brain: Major Regions

The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect various areas...
Brainstem01:19

Brainstem

The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
Neurons as Communicators of the Brain01:22

Neurons as Communicators of the Brain

Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
Neurotransmitters01:31

Neurotransmitters

Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.
Organization of the Brain01:31

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...

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Updated: Jun 30, 2026

Wholemount Immunohistochemistry for Revealing Complex Brain Topography
09:23

Wholemount Immunohistochemistry for Revealing Complex Brain Topography

Published on: April 5, 2012

脊椎動物のグロービンは,脳で発現する.

T Burmester1, B Weich, S Reinhardt

  • 1Institute of Zoology, Johannes Gutenberg University Mainz, Germany. burmeste@mail.uni-mainz.de

Nature
|October 12, 2000
PubMed
まとめ

研究者らは,ニューログロビンという新種の酸素結合タンパク質を,主に脳内に発見した. このタンパク質は,脳組織における酸素の供給を向上させ,脳の酸素ホメオスタシスに関する新しい洞察を提供している可能性がある.

科学分野:

  • バイオケミストリー バイオケミストリー
  • 神経科学は神経科学である.
  • 進化生物学の進化生物学について

背景:

  • ヘモグロビンとミオグロビンは,脊椎動物の酸素輸送と貯蔵で知られている.
  • ヘモグロビンとミオグロビンとは異なる第三のグロービン型が調査されました.

研究 の 目的:

  • 主に脳で発現する新型グロービンタンパク質を特定し,特徴づけること.
  • この新しいグロービンの機能的影響と進化的起源を調査する.

主な方法:

  • 人間とマウスのタンパク質の識別と特徴付け.
  • ヒトの神経球質遺伝子 (NGB) の遺伝子マッピングと分析.
  • 酸素結合親和度の評価. 酸素結合親和度の評価.

主要な成果:

  • ニューログロビンと呼ばれる第三のグロービン型は,ヒトとマウスで特定されました.
  • ニューログロビンは主に脳で発現し,高い酸素親和性を示す.
  • ヒトの神経球質遺伝子 (NGB) は,独特のエクソン・イントロン構造を持ち,染色体14q24に位置しています.

結論:

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In ovo Expression of MicroRNA in Ventral Chick Midbrain
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In ovo Expression of MicroRNA in Ventral Chick Midbrain

Published on: September 16, 2013

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
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In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation

Published on: April 30, 2014

関連する実験動画

Last Updated: Jun 30, 2026

Wholemount Immunohistochemistry for Revealing Complex Brain Topography
09:23

Wholemount Immunohistochemistry for Revealing Complex Brain Topography

Published on: April 5, 2012

In ovo Expression of MicroRNA in Ventral Chick Midbrain
09:19

In ovo Expression of MicroRNA in Ventral Chick Midbrain

Published on: September 16, 2013

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation
09:13

In vivo Interrogation of Central Nervous System Translatome by Polyribosome Fractionation

Published on: April 30, 2014

  • ニューログロビンは,初期のメタゾーン進化の起源を持つ独特のタンパク質ファミリーを表しています.
  • ニューログロビンは,ミオグロビンと似て,脳組織における酸素の供給を増やす役割を果たす可能性があります.
  • ニューログロビンの発見は,酸素結合タンパク質とその機能についての理解を広げています.