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Updated: Jul 10, 2026

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes
09:44

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes

Published on: March 3, 2015

核前mRNAのターンオーバーのための規制された経路の特定

C Bousquet-Antonelli1, C Presutti, D Tollervey

  • 1Wellcome Trust Centre for Cell Biology ICMB, University of Edinburgh, Scotland.

Cell
|October 13, 2000
PubMed
まとめ

研究者らは,未配合のプレメッセンジャーRNA (pre-mRNA) を分解する酵母における核経路を発見した. このプロセスは,エクソソーム複合体とRat1pが関与し,退化とスプライシングのバランスをとることで遺伝子発現を調節します.

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