関連する実験動画
Updated: Jul 18, 2026
16:11
Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
ジャルビック2000ハート (Jarvik 2000 Heart) の最初の恒久性インプラントです
S Westaby1, A P Banning, R Jarvik
1Oxford Heart Centre, John Radcliffe Hospital, UK. swestaby@AHF.org.uk
Lancet (London, England)
|October 19, 2000
まとめ
Jarvik 2000 Heartは,新しい左心室補助装置で,末期心不全の患者にとって有望な結果を示しています. この革新的な装置は,患者の機能を改善し,短期的な合併症なしに症状を緩和しました.
科学分野:
- 心臓病学 心臓病学
- バイオメディカルエンジニアリング
- 医療機器 医療機器について
背景:
- 心不全は,限られたドナー心臓が利用できるため,公衆衛生上の大きな課題となっています.
- 現在の医療療法では,終末期心不全患者の生活の質と寿命が低くなっています.
- 末期性心不全に対する代替的な長期的な解決策の必要性が極めて高い.
研究 の 目的:
- 末期心不全の長期的な解決策としてJarvik 2000 Heartの有効性と安全性を評価する.
- 本来の心機能と心不全症状に対する心室内置器具の影響を評価する.
- 左心室補助装置の全身的効果を調査する.
主な方法:
- Jarvik 2000 Heartのインプラントを伴う将来的な臨床試験が行われました.
- この研究では,ニューヨークハート協会の機能性IV級の拡張性心筋症候群の61歳の男性患者が対象でした.
- 左心室補助装置は,革新的な電源供給システムと心室内置部を備えた.
主要な成果:
- Jarvik 2000 Heartは患者の循環を成功裏に維持し,実用性とユーザーフレンドリー性を実証しました.
- 6週間以内に運動耐性,心筋機能,末端器官機能の有意な改善が観察されました.
- 心不全の症状は解消され,脈圧の継続的な低下による不良効果はなく,血溶は最小限であり,デバイスに関連する合併症はありません.
結論:
- 最初の成功は,終末期心不全の新たな治療方法の可能性を示唆しています.
- 長期の機械的信頼性は,デバイスの最終的な役割を決定する上で決定的に重要です.
- 頭蓋骨に搭載された電源はよく癒され,不注意だった.
関連する概念動画
01:16Heart Valves
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
01:27Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
01:23Holter Monitor: 24-Hour Monitoring
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...