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Updated: May 6, 2026

An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions
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Published on: March 14, 2016

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ICEBERG:インタールイキン-1β生成の新種の阻害剤

E W Humke1, S K Shriver, M A Starovasnik

  • 1Department of Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor 48109, USA.

Cell
|October 29, 2000
PubMed
まとめ

ICEBERGは,カスパース-1を結合することによって,炎症性サイトカインIL-1βの生成を抑制する新しいタンパク質です. この発見は,ICEBERGが炎症反応における負のフィードバックメカニズムとして作用することを示唆しています.

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