関連する実験動画

Updated: Jul 9, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

アクセサリータンパク質はCFTR-CFTRの相互作用を促進し,クロライドチャネル活性を強化する分子メカニズムである

S Wang1, H Yue, R B Derin

  • 1Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Cell
|October 29, 2000
PubMed
まとめ

研究者らはCAP70というタンパク質を発見し,システィック線維症の超膜伝導性調節器 (CFTR) タンパク質と結合した. CFTR 分子を結合することで,塩化物チャネル活性が強化され,CFTR 機能を調節する新しい方法が示唆されています.

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Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

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Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein09:59

Functional Reconstitution and Channel Activity Measurements of Purified Wildtype and Mutant CFTR Protein

Published on: March 9, 2015

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