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Updated: Jul 9, 2026

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ネズミのCTLA-4の構造と,T細胞の応答性を調節する役割

D A Ostrov1, W Shi, J C Schwartz

  • 1Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Science (New York, N.Y.)
|October 29, 2000
PubMed
まとめ

細胞毒性Tリンパ球関連抗原4 (CTLA-4) の二酸化は,T細胞の反応を調節するために重要である. そのユニークな構造により,CTLA-4は複数のB7結合体を結合させ,免疫シナプス内のT細胞活性化に影響を与えます.

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