冠動脈抵抗性動脈の内皮機能不全は,動脈硬化においてテトラヒドロビオプテリンによって改善される

C P Tiefenbacher1, T Bleeke, C Vahl

  • 1Department of Cardiology, University of Heidelberg, Heidelberg, Germany. ctiefenbacher@med.uni-heidelberg.de

Circulation
|November 1, 2000
PubMed
まとめ

テトラヒドロビオプテリン (BH4) レベルが低下すると,動脈硬化で血管機能が低下します. セピアプテリンのサプリメントは,ヒトと豚の動脈の血管拡張を改善し,BH4欠乏が内皮機能障害に寄与することを示しています.

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