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Updated: Jun 10, 2026

Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
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シヌクレイン症の病変における選択的なアルファ-シヌクレイン窒素化による神経変性に関連した酸化的損傷

B I Giasson1, J E Duda, I V Murray

  • 1Center for Neurodegenerative Disease Research and Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|November 4, 2000
PubMed
まとめ

窒素化されたアルファシヌクレインタンパク質は,パーキンソン病および関連する疾患の特徴である脳損傷に蓄積します. この発見は,酸化ストレスとこれらの神経変性シヌクレイン病変の進行を直接関連付けています.

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