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Updated: Jul 12, 2026

Gene Transfer for Ischemic Heart Failure in a Preclinical Model
07:35

Gene Transfer for Ischemic Heart Failure in a Preclinical Model

Published on: May 15, 2011

アデニリルサイクラゼVIをコードするアデノウイルスの冠内伝達により,左心室機能とcAMP生成能力が増加します

N C Lai1, D M Roth, M H Gao

  • 1San Diego VA Healthcare System, Department of Medicine, San Diego, CA, USA.

Circulation
|November 9, 2000
PubMed
まとめ

アデニリルサイクラース型VI (AC(VI)) をコードするアデノウイルスを用いた遺伝子転送により,豚の心臓機能が著しく改善されました. この心臓遺伝子療法は,左心室の機能と心臓出力の持続的な増加を副作用なく実証しました.

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