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Updated: Jul 9, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

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Published on: March 22, 2012

トール/インタールユーキン-1受容体ドメインによる信号伝導の構造的基礎

Y Xu1, X Tao, B Shen

  • 1Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

Nature
|November 18, 2000
PubMed
まとめ

トール型受容体 (TLRs) は免疫の鍵である. TIRドメインの特定の突然変異は,MyD88アダプター分子との相互作用を防止し,宿主の防御に影響を与えることによって,免疫信号伝達を妨害します.

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