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Updated: Jun 7, 2026

Analyzing Large Protein Complexes by Structural Mass Spectrometry
15:35

Analyzing Large Protein Complexes by Structural Mass Spectrometry

Published on: June 20, 2010

11Sのレギュレータによる20Sプロテアソームの活性化のための構造的基礎

F G Whitby1, E I Masters, L Kramer

  • 1Biochemistry Department, University of Utah, Salt Lake City 84132, USA.

Nature
|November 18, 2000
PubMed
まとめ

細胞のタンパク質分解に不可欠な20Sプロテアソームは,11S調節体 (PA26) を通してゲートを開きます. この構造の変化はペプチド産物の放出を促進し,主要な組織適合性複合体のクラスI分子生産に影響を与えます.

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