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Updated: May 13, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
07:24

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

Published on: April 8, 2013

心臓アロ移植における亜鉛媒介によるアポトーシスの減少

M H Kown1, T Van der Steenhoven, F G Blankenberg

  • 1Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305-5247, USA.

Circulation
|November 18, 2000
PubMed
まとめ

亜鉛塩化物 (ZnCl2) は,カスパース-3活性を阻害することによって,急性心臓アロ移植拒絶時のアポトーシスを効果的に減少させます. この研究は,アポトーシスの投与量依存的減少と,治療されたラットにおける移植の生存率の改善を示しています.

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