感染症性内心炎の危険因子:口腔衛生と非口腔曝露
B L Strom1, E Abrutyn, J A Berlin
1Department of Biostatistics and Epidemiology and Center for Clinical Epidemiology and Biostatistics, Division of General Internal Medicine, University of Pennsylvania, Philadelpha 19104-6021, USA. Bstrom@cceb.med.upenn.edu
Circulation
|January 11, 2000
まとめ
感染症性内心炎 (IE) は,一般的な医療処置ではなく,重度の腎疾患と糖尿病に関連しています. 毎日のフロスは,歯の植物からIEのリスクをわずかに減らすことができます.
科学分野:
- 心臓病学 心臓病学
- 感染症 感染症は感染症です.
- エピデミオロジー エピデミオロジー
背景:
- 感染症性内心炎 (IE) の危険因子は十分に理解されていません.
- 特定の危険因子を特定することは,予防と管理に極めて重要です.
研究 の 目的:
- 各種疾患,処置,およびコミュニティで発症した感染症性内心炎 (IE) の関連性を調査する.
- 人口ベースの研究でIEの可変および不可変の危険因子を特定する.
主な方法:
- 1988年から1990年にかけて,フィラデルフィア地区で人口ベースの症例対照研究が行われました.
- コミュニティで発症したIE症例 (静脈注射薬物使用を除く) は,マッチしたコミュニティの住民と比較した.
- リスク要因は,インタビューを通じて評価され,専門家の医療記録のレビューによって確認されました.
主要な成果:
- 重度の腎疾患 (OR=16.9) と糖尿病 (OR=2.7) は,IEリスクの増加と有意に関連していました.
- 皮膚の細菌系から発症したIEの患者は,以前に静脈注射液を使用した割合 (OR=6.7) と皮膚感染症の割合が高かった.
- IEと最近の肺,胃腸,心臓,またはGUの手順,または手術との間には関連性が見つかりませんでした.
- 歯のない患者は,毎日歯線を磨かない歯を持つ患者と比較して,歯の植物からIEのリスクが低かった.
結論:
- 感染症性内心炎 (IE) は,重度の腎疾患や糖尿病などの特定の基礎疾患と関連しています.
- 最近の医療や歯科の手術は,この研究で有意なリスク要因として特定されていません.
- 毎日の歯磨きは,IEのリスクの限界値低下を示し,潜在的な予防策を示唆しました.
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