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Updated: May 8, 2026

Xenopus laevis as a Model to Identify Translation Impairment
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普遍的な翻訳開始因子IF2/eIF5BのX線構造:GDPとGTPを結合する形状の変化

A Roll-Mecak1, C Cao, T E Dever

  • 1Laboratories of Molecular Biophysics The Rockefeller University 10021, New York, NY 10021, USA.

Cell
|December 15, 2000
PubMed
まとめ

普遍的な翻訳開始因子IF2/eIF5Bに関する構造的な洞察は,そのカップの形とGTPaseの機能を明らかにします. X線構造は,IF2/eIF5Bがすべての生命体におけるタンパク質合成の重要なステップをどのように促進するかを明らかにしています.

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