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Updated: Jul 10, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
07:23

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

ベータアレスティン-2によるミュオピオイド受容体の無敏感化は,モルヒンの耐性を決定するが,依存性を決定するものではない

L M Bohn1, R R Gainetdinov, F T Lin

  • 1Howard Hughes Medical Institute Laboratories, Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature
|December 29, 2000
PubMed
まとめ

ベータアレスティン-2は,モルヒネの耐性には極めて重要です. ベータアレスティン-2 が欠けているマウスは,モルヒネに対する耐性を培うことはできません.

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