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Updated: May 5, 2026

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
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ベータ-カタニン/Tcf複合体の結晶構造

T A Graham1, C Weaver, F Mao

  • 1Department of Biological Structure University of Washington 98195, Seattle, WA, USA.

Cell
|January 4, 2001
PubMed
まとめ

研究者は,Tcf3-CBDに結合するβ-カテニンの結晶構造を決定し,重要な結合部位を明らかにしました. この発見は,Wnt信号伝達経路を標的とした分子薬物設計の可能性を秘めています.

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