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Updated: Jul 6, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

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DNA-PKcsは,免疫刺激性DNAによる先天性免疫の活性化に必要なものです

W Chu1, X Gong, Z Li

  • 1The Sam and Rose Stein Institute for Research on Aging, University of California, San Diego 9500 Gilman Drive 92093, La Jolla, CA, USA. wmchu@ucsd.edu

Cell
|January 4, 2001
PubMed
まとめ

バクテリアのDNAと合成免疫刺激性オリゴデオキシリボヌクレオチド (ISS-ODN) は,先天的免疫を活性化する. DNA-PKcsとIKKbetaは,このシトカイン応答に不可欠であり,DNA修復と免疫シグナル伝達を結びつける.

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