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Updated: Jul 19, 2026

Spatial and Temporal Analysis of Active ERK in the C. elegans Germline
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C. elegans vulval の発達中に,MAP キナーゼフォスファタゼ LIP-1 を経由した RAS シグナリングのノッチ阻害

T Berset1, E F Hoier, G Battu

  • 1Division of Cancer Research, Department of Pathology, University of Zürich, Schmelzbergstrasse 12, CH-8091 Zürich, Switzerland.

Science (New York, N.Y.)
|February 13, 2001
PubMed
まとめ

C. elegans vulvalの発達において,LIP-1はレセプターチロシンキナーゼ/RAS/ミトゲン活性化タンパク質キナーゼとNotchシグナリングをリンクする. これは,隣接する細胞におけるプライマリー運命を特定することを阻害することによって,適切な細胞運命を保証します.

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