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Updated: Jul 15, 2026

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

LPSによるTNF-α誘導は,TPL2/ERK依存の経路を通じて,ポストトランスクリプションで調節される

C D Dumitru1, J D Ceci, C Tsatsanis

  • 1Kimmel Cancer Center, Department of Microbiology and Immunology, Thomas Jefferson University, 233 S. 10th Street, Philadelphia, PA 19107, USA.

Cell
|February 13, 2001
PubMed
まとめ

Tpl2のノックアウトマウスは,腫瘍死滅因子アルファ (TNF-alpha) の産生が低下し,病理学に対する抵抗性を示した. Tpl2シグナリングは,特にTNF-α mRNA輸送を促進し,その誘導に影響を与えます.

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Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity

Published on: January 7, 2019

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells10:57

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells

Published on: January 12, 2020

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