関連する実験動画

Updated: May 5, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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オステオブラストにおけるTobによるBMP/Smadシグナル伝達の負の調節

Y Yoshida1, S Tanaka, H Umemori

  • 1Department of Oncology, The Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

Cell
|February 13, 2001
PubMed
まとめ

トブタンパク質は,骨芽細胞における骨形態遺伝タンパク質 (BMP) /Smadシグナル伝達を阻害することによって,骨形成を否定的に調節する. トブ遺伝子を削除すると,オステオブラストの数と骨質が増加し,トブが強調されます.

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