関連する実験動画

Updated: May 12, 2026

Combining Intravital Fluorescent Microscopy (IVFM) with Genetic Models to Study Engraftment Dynamics of Hematopoietic Cells to Bone Marrow Niches
11:06

Combining Intravital Fluorescent Microscopy (IVFM) with Genetic Models to Study Engraftment Dynamics of Hematopoietic Cells to Bone Marrow Niches

Published on: March 21, 2017

骨髄性系統でJunB発現が欠けているマウスにおける粒細胞原始体の増加による慢性骨髄性白血病

E Passegué1, W Jochum, M Schorpp-Kistner

  • 1Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

Cell
|February 13, 2001
PubMed
まとめ

JunBは,血液細胞の発達 (骨髄形成) を制御するために不可欠です. 欠乏すると,マウスの骨髄性白血病を引き起こし,JunBを強調する.

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Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:
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Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...