脳卒中の量と心臓の出力と身体の組成の関係: 強い心臓の研究
T Collis1, R B Devereux, M J Roman
1Cornell Medical Center, New York, NY, USA. rbdevere@med.cornell.edu
Circulation
|February 15, 2001
まとめ
ストローク・ボリューム (SV) と心臓出力 (CO) は,体重だけでなく,脂肪フリー質量 (FFM) と最も強く関連しています. 増加したFFM,特に肥満では,より高いSVとCOの主なドライバーです.
科学分野:
- 心臓病学 心臓病学
- 生理学 生理学とは
- ボディコンポジション分析 分析
背景:
- 心臓の出力 (CO) は,栄養素の供給に不可欠です.
- 大集団における体構成との関係における脳卒中量 (SV) とCOに関するデータは限られている.
研究 の 目的:
- 大規模な集団サンプルで,脳卒中量 (SV) と心電量 (CO) と身体構成との関係を調査する.
- 無脂肪質量 (FFM) と脂肪質量を含む,SVとCOの主要な決定因子を特定する.
主な方法:
- ドップラーと2Dエコーカルディオグラフィーとバイオエレクトリックインピデンスを用いて,Strong Heart Studyの2744人の参加者を対象とした.
- SVとCOを計算し,FFM,脂肪量,人口統計学的変数との相関を分析した.
- SVとCOの独立した相関値を決定するために多変量分析を使用しました.
主要な成果:
- SVとCOは男性と肥満者においてより高かったが,FFMまたは体表面積の正常化によりこれらの差異は減少した.
- FFMは脂肪の量,血圧,糖尿病,または年齢よりも,SVとCOのより強い相関関係でした.
- 多変量分析により,FFMが最強の相関値であると確認され,脂肪質量,静脈圧,年齢,および特定の薬剤が次いであります.
結論:
- 集団ベースのサンプルでは,SVとCOは,他の測定変数よりもFFMと強く関連しています.
- 増加したFFMは,特に肥満では,増加したSVとCOの主な決定因子であるようです.
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