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Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

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Updated: Jul 13, 2026

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
09:19

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

遺伝子治療と幹細胞治療は,

E H Kaji1, J M Leiden

  • 1Abbott Laboratories, Department of Executive, Bldg AP6D, 100 Abbott Park Rd, Abbott Park, IL 60064, USA.

JAMA
|February 15, 2001
PubMed
まとめ

遺伝子治療と幹細胞治療は,遺伝的および獲得性疾患に対する潜在的な治療法を提供します. ベクトル開発,幹細胞生物学,および倫理的検討に関するさらなる研究は,それらの完全な治療的約束を実現するために不可欠です.

科学分野:

  • バイオメディカルサイエンスの科学
  • 再生医学は再生医学である.
  • 分子生物学は分子生物学である.

背景:

  • 遺伝子治療と幹細胞治療は,さまざまなヒト疾患の治療に有望であることを示しています.
  • 遺伝子治療は,遺伝子識別と新しい配送ベクトルを通じて,著しい進歩を遂げています.
  • 幹細胞の研究は,幹細胞の可塑性に関する発見と,ヒト胚性幹細胞の作成によって進歩しました.

研究 の 目的:

  • 遺伝子治療と幹細胞治療の進展と可能性を検討する.
  • 遺伝子識別,ベクトル発育,幹細胞分離および可塑性における進歩を強調する.
  • フィールドでの残った課題と倫理的検討を強調する.

主な方法:

  • 遺伝子および幹細胞療法に関する現在の文献のレビュー.
  • 遺伝子治療のための遺伝子識別とベクトル開発における進歩の分析.
  • 幹細胞の分離,可塑性,および治療の可行性の検討.

主要な成果:

  • 遺伝子治療は,改良された遺伝子識別と配送システムにより進歩しています.
  • 幹細胞治療は実現可能であり,幹細胞の可塑性やヒト胚性幹細胞の作成に関する発見によって支持されています.
キーワード:
生物医学および行動研究遺伝学と生殖について

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Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells
11:16

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells

Published on: February 15, 2019

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

関連する実験動画

Last Updated: Jul 13, 2026

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies
09:19

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells
11:16

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells

Published on: February 15, 2019

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

  • ベクター開発と幹細胞生物学における重要な研究は依然として残っています.

    • 結論:

    • 遺伝子治療と幹細胞治療は,幅広い病気の治療に相当な希望を示しています.
    • ベクター開発と幹細胞生物学における技術的な課題を克服するために,さらなる研究が不可欠です.
    • これらの先進的な治療法を取り巻く倫理的な問題は,慎重に検討し,議論する必要があります.