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Updated: May 15, 2026

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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Published on: July 25, 2019

悪性メラノーマにおけるアポトーシスエフェクタ Apaf-1 の無活性化

M S Soengas1, P Capodieci, D Polsky

  • 1Cold Spring Harbor Laboratory, New York 11724, USA.

Nature
|February 24, 2001
PubMed
まとめ

転移性メラノーマは,プログラム細胞死のための重要なタンパク質であるApaf-1をしばしば無効化する. Apaf-1レベルを回復させることで,化学抵抗性メラノーマ細胞を治療に再敏感化することができます.

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