エピレプシーと抗薬の神経心理学的効果

P Kwan¹, M J Brodie

¹University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland.

Lancet (London, England)

|February 24, 2001

まとめ

とその治療は,認知と行動に影響を与える可能性があります. 抗薬は発作を助けますが,神経心理学的機能に影響を与える可能性があるため,個別評価は極めて重要です.

科学分野:

神経学神経学とは
神経心理学の神経心理学について

背景:

とその治療は,認知および行動障害と関連しています.
エピレプシーの患者は,神経病理学,発作,抗薬 (AED),および心理社会的問題などの複雑な要因のために,神経心理学的機能障害の割合が高くなります.

研究の目的:

エピレプシーにおける認知および行動的結果に対する多面的な影響をレビューする.
これらの効果を研究する際の方法論的課題を強調する.
個別化された患者評価の必要性を強調する.

主な方法:

エピレプシー,神経心理学,治療効果に関する既存の研究の文献レビューと合成.
エピレプシー患者における認知および行動機能障害に寄与する要因の分析.
現在の研究における方法論的限界についての議論.

主要な成果:

における認知および行動的欠陥は,神経病理学,ニューロン放電,AED,および心理社会的要因の複雑な相互作用から生じる.
標準化試験の欠如,サンプルサイズが小さい,統計分析が不十分といった方法論的な問題は,研究を妨げています.
AEDは神経心理学的機能に悪影響を及ぼしますが,発作制御は認知と行動を改善することができます.

結論:

個別的評価は,とその治療の認知および行動的影響を理解し,管理するために不可欠です.
各患者に対する様々な要因の異なる影響を認識することは,効果的な臨床管理に不可欠です.

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