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Updated: Jul 15, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

異例のCFTR依存のHCO3-輸送が,システィックフィブロシスに関連した変異で認められる

J Y Choi1, D Muallem, K Kiselyov

  • 1Department of Physiology, The University of Texas Southwestern Medical Center, Dallas 75390, USA.

Nature
|March 10, 2001
PubMed
まとめ

胞性線維症 (CF) は,胞性線維症のトランスメブラン伝導性調節器 (CFTR) の変異から生じる. CFTRの二酸化炭素 (HCO3-) 輸送の障害は,塩化物 (Cl-) 経路機能だけでなく,CFの病原性には極めて重要です.

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