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Updated: Jun 17, 2026

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
10:14

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

5'-デオキシリボースリン酸リン酸塩酵素がヒトDNAポリメラーゼイオータの活性化作用を in vitroで示しています

K Bebenek1, A Tissier, E G Frank

  • 1Laboratory of Molecular Genetics and, Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

Science (New York, N.Y.)
|March 17, 2001
PubMed
まとめ

人間のDNAポリメラーゼイオタ (pol iota) は,独特の5'-デオキシリボゼリン酸 (dRP) リアース活性を持っています. この酵素はDNAの塩基不一致を修復するのに役立ちますが,特殊な塩基切除修復経路の役割を示唆しています.

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