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Updated: May 5, 2026

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins

Published on: September 28, 2012

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BARD1-CstF-50の相互作用は,mRNA 3'端の形成をDNA損傷と腫瘍抑制と結びつける

F E Kleiman1, J L Manley

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|March 21, 2001
PubMed
まとめ

BRCA1関連タンパク質BARD1 (BARD1) は,CstFポリデニレーション因子と相互作用し,DNA損傷中にmRNA処理を阻害する. mRNA処理とDNA修復の間のこのリンクは,腫瘍抑制における役割を示唆しています.

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