関連する実験動画

Updated: May 12, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
08:47

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

Published on: March 5, 2018

XIAPによるカスパース7抑制の構造的基礎

J Chai1, E Shiozaki, S M Srinivasula

  • 1Department of Molecular Biology, Princeton University, Lewis Thomas Laboratory, Washington Road, Princeton, NJ 08544, USA.

Cell
|March 21, 2001
PubMed
まとめ

アポトーシス阻害剤 (IAP) タンパク質は,カスパスを阻害することによって細胞死を阻害する. この研究は,XIAPペプチド結合カスペーゼ-7の結晶構造を明らかにし,新しいカスペーゼ阻害剤を設計するための洞察を提供します.

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