人間の胎児における心臓の出力と血流の中央分布
1Department of Obstetrics and Gynecology, University of Tuebingen, Tuebingen, Germany. grmielke@med.uni-tuebingen.de
Circulation
|March 29, 2001
まとめ
この研究は,胎児の心臓出力基準範囲を確立し,妊娠13週から妊娠期までの血流分布における右心臓の有意な優位性を明らかにしています.
科学分野:
- 胎児生理学 胎児生理学
- 心血管の超音波検査です.
- ペディアトリック・カルディオロジー
背景:
- 胎児の心臓出力の基準範囲を確立することは,正常な心血管発達の理解に不可欠です.
- 胎児の血流分布を調査することは,先天性心疾患の診断に不可欠です.
研究 の 目的:
- 人間の胎児における左心と右心出力の基準範囲を確立する.
- 胎児の血流の分布を卵巣孔,大動脈管,肺床を通して調べるため.
主な方法:
- 222人の正常な胎児 (妊娠13~41週) を対象とした前向きな研究.
- 高解像度カラードップラー超音波を用いた測定.
- 血管直径と時速積分を用いて計算された心臓出力とドクトルフロー.
主要な成果:
- 妊娠年齢特有の基準範囲は,心臓の出力量と管道血流量のために確立されています.
- 右心電量 (59%) は,左心電量 (41%) を支配しています.
- 管道血流 (46%),肺流 (11%),門卵巣流 (33%) は,二心室出力に対して定量化されています.
結論:
- この研究は,胎児の心臓出力と中央血流分布の重要な基準範囲を提供します.
- 明らかに右心臓の優位性は胎児の循環に顕著です.
- 推定肺血流と心臓の出力比は,胎児の羊の研究で報告された値より高い.
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