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Updated: Jun 28, 2026

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates
12:23

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates

Published on: March 18, 2011

ミュータントのドロソフィラインスリン受容体のホモログで,寿命を延ばし,神経内分泌機能を損なう

M Tatar1, A Kopelman, D Epstein

  • 1Brown University, Providence, RI 02912, USA., University of Massachusetts, Amherst, MA 01003, USA. Marc_Tatar@Brown.edu

Science (New York, N.Y.)
|April 9, 2001
PubMed
まとめ

ドロソフィラのインスリン類似受容体 (InR) 遺伝子の変異は,矮身症を引き起こし,ハエの寿命を大幅に延長します. これは,InR経路によって媒介される若年ホルモン欠乏が,老化に鍵となることを示唆しています.

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