高齢者の間で適度なアルコール摂取と心不全のリスク

J L Abramson¹, S A Williams, H M Krumholz

¹Emory University School of Medicine, Department of Medicine, Division of Cardiology, 1256 Briarcliff Rd NE, Suite 1 North, Atlanta, GA 30306, USA. jerome@ecor.cardio.emory.edu

JAMA

|April 20, 2001

まとめ

適度なアルコール摂取は,高齢者の心不全のリスク低下と関連しています. この発見は,他の健康要因と心筋梗塞 (MI) のリスクを考慮したとしても当てはまります.

科学分野:

心臓病学心臓病学
ゲリアトリクスゲリアトリクス
公衆衛生は公衆衛生である.

背景:

過剰なアルコール摂取は,心不全の既知の危険因子です.
心不全のリスクに対する適度なアルコール摂取の影響は不明である.

研究の目的:

高齢者における適度なアルコール摂取と心不全のリスクとの関連性を調査する.
この関連が心筋梗塞 (MI) リスクとは独立しているかどうかを判断する.

主な方法:

2235人の高齢者参加者を対象とした前向きなコホート研究で,最大14年間追跡調査が行われました.
アルコールの消費量は,ベースライン前の1ヶ月の摂取量に基づいて評価されました.
心不全イベント (致命的または非致命的) は,主要なアウトカムとして追跡されました.

主要な成果:

適度なアルコール摂取量 (1〜70オンス/月) の増加は,心不全率の低下と関連していました.
心不全の調整された相対リスクは,非飲酒者に対して1.00,0.79,0.53,1〜20オンス,21〜70オンスであった.
適度なアルコール摂取量を増やすことで心不全のリスクが低下する傾向は,統計的に有意であった (P=.02).

結論:

適度なアルコール摂取は,高齢者の心不全のリスク低下と関連しています.
この関連性は,いくつかの混同要因から独立しています.
心不全に対する保護効果は,単に心筋梗塞のリスクの低下によるものではないようです.

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